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Relevant publications

Relevant Publications

Publications of Prof. Dr. med. Christian Bogdan since 2014

 

Experimental mouse leishmaniasis
  1. Bogdan C, Islam N.-A-K., Barinberg D, Soulat D, Schleicher U and Rai B. The immunomicrotope of Leishmania control and persistence. Trends in Parasitology 2024 (in press)
  2. Lai C, Heinemann J, Schleicher U, Schett G, Bogdan C, Bozec A, Soulat D. Chronic Systemic Infection of Mice with Leishmania infantum Leads to Increased Bone Mass. J Bone Miner Res. 2023 Jan;38(1):86-102. doi: 10.1002/jbmr.4733. Epub 2022 Nov 16.
  3. Sasse C, Barinberg D, Obermeyer S, Debus A, Schleicher U, Bogdan C. Eosinophils, but Not Type 2 Innate Lymphoid Cells, Are the Predominant Source of Interleukin 4 during the Innate Phase of Leishmania major Infection.  Pathogens 2022 Jul 25;11(8):828. doi: 10.3390/pathogens11080828.
  4. Bogdan C.Macrophages as host, effector and immunoregulatory cells in leishmaniasis: Impact of tissue micro-environment and metabolism.  Cytokine X. 2020 Oct 12;2(4):100041. doi: 10.1016/j.cytox.2020.100041. eCollection 2020 Dec.
  5. Paduch K, Debus A, Rai B, Schleicher U, Bogdan C. Resolution of cutaneous leishmaniasis and persistence of Leishmania major in the absence of arginase 1. J Immunol. 2019 Mar 1;202(5):1453-1464. doi: 10.4049/jimmunol.1801249. Epub 2019 Jan 21.
  6. Bogdan C, Debus A, Sebald H, Rai B, Schäfer J, Obermeyer S, Schleicher U. Experimental Cutaneous Leishmaniasis: Mouse Models for Resolution of Inflammation Versus Chronicity of Disease. Methods Mol Biol. 2019;1971:315-349. doi: 10.1007/978-1-4939-9210-2_18.
  7. Messlinger H, Sebald H, Heger L, Dudziak D, Bogdan C and Schleicher U. (2018). Monocyte-derived signals activate human natural killer cells in response to Leishmania  parasites. Frontiers in Immunology epublished January 24, 2018: doi: 10.3389/fimmu.2018.00024.
  8. Schleicher U, Liese J, Justies N, Mischke T, Haeberlein S, Sebald H, Kalinke U, Weiss S and Bogdan C. (2018). Type I interferon signaling is required for CpG-oligodesoxy-nucleotide-induced control of Leishmania major, but not for spontaneous cure of subcutaneous cure of primary and secondary L. major infection. Frontiers in Immunology epublished January 11, 2018: doi: 10.3389/ fimmu.2018.00079.
  9. Leitherer S, Clos J, Liebler-Tenorio EM, Schleicher U, Bogdan C, Soulat D. Characterization of the Protein Tyrosine Phosphatase LmPRL-1 Secreted by Leishmania major via the Exosome Pathway.  Infect Immun. 2017 Jul 19;85(8):e00084-17. doi: 10.1128/IAI.00084-17. Print 2017 Aug.
  10. Schatz V, Strüssmann Y, Mahnke A, Schley G, Waldner M, Ritter U, Wild J, Willam C, Dehne N, Brüne B, McNiff JM, Colegio OR, Bogdan C, Jantsch J. Myeloid Cell-Derived HIF-1α Promotes Control of Leishmania major.  J Immunol. 2016 Nov 15;197(10):4034-4041. doi: 10.4049/jimmunol.1601080. Epub 2016 Oct 17.
  11. Schleicher U., Paduch K., Debus A., Obermeyer S., König T., Kling J.C., Ribechini E., Dudziak D., Mougiakakos D., Murray P.J., Ostuni R., Körner H. and Bogdan C  (2016). TNF-Mediated Restriction of Arginase 1 Expression in Myeloid Cells Triggers Type 2 NO Synthase Activity at the Site of Infection. Cell Reports 15: 1062-75.
  12. Fromm PD, Kling JC, Remke A, Bogdan C, Körner H. Fatal Leishmaniasis in the Absence of TNF Despite a Strong Th1 Response. Front Microbiol. 2016 Jan 22;6:1520. doi: 10.3389/fmicb.2015.01520. eCollection 2015.
  13. Jantsch J, Schatz V, Friedrich D, Schröder A, Kopp C, Siegert I, Maronna A, Wendelborn D, Linz P, Binger KJ, Gebhardt M, Heinig M, Neubert P, Fischer F, Teufel S, David JP, Neufert C, Cavallaro A, Rakova N, Küper C, Beck FX, Neuhofer W, Muller DN, Schuler G, Uder M, Bogdan C, Luft FC, Titze J. Cutaneous Na+ storage strengthens the antimicrobial barrier function of the skin and boosts macrophage-driven host defense.  Cell Metab. 2015 Mar 3;21(3):493-501. doi: 10.1016/j.cmet.2015.02.003.
  14. Mahnke A, Meier RJ, Schatz V, Hofmann J, Castiglione K, Schleicher U, Wolfbeis OS, Bogdan C, Jantsch J. Hypoxia in Leishmania major skin lesions impairs the NO-dependent leishmanicidal activity of macrophages. J Invest Dermatol. 2014 Sep;134(9):2339-2346. doi: 10.1038/jid.2014.121. Epub 2014 Feb 28
  15. Bogdan C (2015) Nitric oxide synthase in innate and adaptive immunity: an update. Trends Immunol 36: 161-178
  16. Schleicher U, Liese J, Knippertz I, Kurzmann C, Hesse A, Heit A, Fischer JA, Weiss S, Kalinke U, Kunz S, Bogdan C (2007). NK cell activation in visceral leishmaniasis requires TLR9, myeloid DCs, and IL-12, but is independent of pDCs. J Exp Med. 204: 893-906.

 

Clinical leishmaniasis (diagnostics, therapy, epidemiology)
  1. Debus D, Genç S, Kurz P, Holzer M, Bauer K, Heimke-Brinck R, Baier M, Sebald H, Debus A, Bogdan C*, Stahl KW*. Case Report: Local Treatment of a Leishmania tropica Infection in a Syrian Child with a Novel Filmogenic Preparation of Pharmaceutical Sodium Chlorite (LeiProtect®). Am J Trop Med Hyg. 2022 Jan 10;106(3):857-860. doi: 10.4269/ajtmh.21-0962. (* shared senior authorship)
  2. Scholl S, Schuster D, Technau-Hafsi K, Stete K, Rieg S, May AM, Bogdan C, Schauer F. Case report: Cutaneous pseudolymphoma caused by a Leishmania infantum infection in a patient treated with anti-TNF antibody for plaque psoriasis. Front Med (Lausanne). 2022 Dec 2;9:1055703. doi: 10.3389/fmed.2022.1055703. eCollection 2022
  3. Burmann SN, Sunderkötter C, Böer-Auer A, Oellig F, Fischer M, Bogdan C, Michalowitz AL, Kreuter A. Relevante Aspekte zur kutanen Leishmaniose auf Mallorca. J Dtsch Dermatol Ges. 2022 Apr;20(4):530-532. doi: 10.1111/ddg.14768_g.
  4. Hobelsberger S, Krauß MP, Bogdan C, Aschoff R. Successful treatment of cutaneous leishmaniasis with simulated daylight photodynamic therapy.  Hautarzt. 2022 May;73(5):376-378. doi: 10.1007/s00105-021-04852-y. Epub 2021 Jul 2.
  5. Busch D, Bogdan C, Erfurt-Berge C. Clinical Manifestation of Cutaneous Leishmaniasis Following a Mechanical Trauma. Int J Low Extrem Wounds. 2023 Mar;22(1):146-148. doi: 10.1177/1534734620968964. Epub 2020 Nov
  6. Molkara S, Poursoltani E, Stahl KW, Maleki M, Khamesipour A, Bogdan C, Salehi M, Goyonlo VM. Salvage therapy with Sodium chlorosum (formerly DAC N-055) for cases of refractory lupoid cutaneous leishmaniasis: results from a compassionate use study with 0.09% Sodium chlorosum in amphiphilic basic cream. BMC Infect Dis. 2019 Nov 28;19(1):1005. doi: 10.1186/s12879-019-4518-x.
  7. Kirchberger MC, Schliep S, Bogdan C.Rhinophyma-Like Cutaneous Leishmaniasis due to Leishmania aethiopica Treated Successfully with Liposomal Amphotericin B. Am J Trop Med Hyg. 2019 Feb;100(2):231-232. doi: 10.4269/ajtmh.18-0578.
  8. Bode SF, Bogdan C, Beutel K, Behnisch W, Greiner J, Henning S, Jorch N, Jankofsky M, Jakob M, Schmid I, Veelken N, Vraetz T, Janka G, Ehl S, Lehmberg K. Hemophagocytic lymphohistiocytosis in imported pediatric visceral leishmaniasis in a nonendemic area. J Pediatr. 2014 Jul;165(1):147-153.e1. doi: 10.1016/j.jpeds.2014.03.047. Epub 2014 May 3.
  9. Jebran AF, Schleicher U, Steiner R, Wentker P, Mahfuz F, Stahl HC, Amin FM, Bogdan C*, Stahl KW*. Rapid healing of cutaneous leishmaniasis by high-frequency electrocauterization and hydrogel wound care with or without DAC N-055: a randomized controlled phase IIa trial in Kabul.  PLoS Negl Trop Dis. 2014 Feb 13;8(2):e2694. doi: 10.1371/journal.pntd.0002694. eCollection 2014 Feb. (*shared senior authorship)
  10. Stahl HC, Ahmadi F, Schleicher U, Sauerborn R, Bermejo JL, Amirih ML, Sakhayee I, Bogdan C, Stahl KW.A randomized controlled phase IIb wound healing trial of cutaneous leishmaniasis ulcers with 0.045% pharmaceutical chlorite (DAC N-055) with and without bipolar high frequency electro-cauterization versus intralesional antimony in Afghanistan. BMC Infect Dis. 2014 Nov 25;14:619. doi: 10.1186/s12879-014-0619-8.

 

Immunology (incl. infectious disease immunology)
  1. Wrage M, Holland T, Nüse B, Kaltwasser J, Fröhlich J, Arnold H, Gießler C, Flamann C, Bruns H, Berges J, Daniel C, Hoffmann MH, Anish C, Seeberger PH, Bogdan C, Dettmer K, Rauh M, Mattner J. Cell type-specific modulation of metabolic, immune-regulatory, and anti-microbial pathways by CD101. Mucosal Immunol. 2024 Jun 18:S1933-0219(24)00058-8. doi: 10.1016/j.mucimm.2024.06.004. Online ahead of print.
  2. Kohl L, Siddique MNAA, Bodendorfer B, Berger R, Preikschat A, Daniel C, Ölke M, Liebler-Tenorio E, Schulze-Luehrmann J, Mauermeir M, Yang KT, Hayek I, Szperlinski M, Andrack J, Schleicher U, Bozec A, Krönke G, Murray PJ, Wirtz S, Yamamoto M, Schatz V, Jantsch J, Oefner P, Degrandi D, Pfeffer K, Mertens-Scholz K, Rauber S, Bogdan C, Dettmer K, Lührmann A, Lang R. Macrophages inhibit Coxiella burnetii by the ACOD1-itaconate pathway for containment of Q fever. EMBO Mol Med. 2023 Feb 8;15(2):e15931. doi: 10.15252/emmm.202215931. Epub 2022 Dec 7.
  3. Brigo N, Pfeifhofer-Obermair C, Tymoszuk P, Demetz E, Engl S, Barros-Pinkelnig M, Dichtl S, Fischer C, Valente De Souza L, Petzer V, von Raffay L, Hilbe R, Berger S, Seifert M, Schleicher U, Bogdan C, Weiss G. Cytokine-Mediated Regulation of ARG1 in Macrophages and Its Impact on the Control of Salmonella enterica Serovar Typhimurium Infection. Cells. 2021 Jul 19;10(7):1823. doi: 10.3390/cells10071823.
  4. Müller BJ, Westheider A, Birkner K, Seelig B, Kirschnek S, Bogdan C, von Loewenich FD. Anaplasma phagocytophilum Induces TLR- and MyD88-Dependent Signaling in In Vitro Generated Murine Neutrophils. Front Cell Infect Microbiol. 2021 Mar 4;11:627630. doi: 10.3389/fcimb.2021.627630. eCollection 2021.
  5. Hayek I, Schatz V, Bogdan C, Jantsch J, Lührmann A. Mechanisms controlling bacterial infection in myeloid cells under hypoxic conditions. Cell Mol Life Sci. 2021 Mar;78(5):1887-1907. doi: 10.1007/s00018-020-03684-8. Epub 2020 Oct 30.
  6. Baier J, Gänsbauer M, Giessler C, Arnold H, Muske M, Schleicher U, Lukassen S, Ekici A, Rauh M, Daniel C, Hartmann A, Schmid B, Tripal P, Dettmer K, Oefner PJ, Atreya R, Wirtz S, Bogdan C, Mattner J. Arginase impedes the resolution of colitis by altering the microbiome and metabolome. J Clin Invest. 2020 Nov 2;130(11):5703-5720. doi: 10.1172/JCI126923.
  7. Fuchs M, Kreutzer FP, Kapsner LA, Mitzka S, Just A, Perbellini F, Terracciano CM, Xiao K, Geffers R, Bogdan C, Prokosch HU, Fiedler J, Thum T, Kunz M. Integrative Bioinformatic Analyses of Global Transcriptome Data Decipher Novel Molecular Insights into Cardiac Anti-Fibrotic Therapies. Int J Mol Sci. 2020 Jul 2;21(13):4727. doi: 10.3390/ijms21134727.
  8. Abdissa K, Ruangkiattikul N, Ahrend W, Nerlich A, Beineke A, Laarmann K, Janze N, Lobermeyer U, Suwandi A, Falk C, Schleicher U, Weiss S, Bogdan C, Goethe R. Relevance of inducible nitric oxide synthase for immune control of Mycobacterium avium subspecies paratuberculosis infection in mice. Virulence. 2020 Dec;11(1):465-481. doi: 10.1080/21505594.2020.1763055.
  9. Kindermann M, Knipfer L, Obermeyer S, Müller U, Alber G, Bogdan C, Schleicher U, Neurath MF, Wirtz S. Group 2 Innate Lymphoid Cells (ILC2) Suppress Beneficial Type 1 Immune Responses During Pulmonary Cryptococcosis. Front Immunol. 2020 Feb 14;11:209. doi: 10.3389/fimmu.2020.00209. eCollection 2020.
  10. Cossarizza A, Chang HD, Radbruch A, Acs A, Adam D, Adam-Klages S, Agace WW, Aghaeepour N, Akdis M, Allez M, Almeida LN, Alvisi G, Anderson G, Andrä I, Annunziato F, Anselmo A, Bacher P, Baldari CT, Bari S, Barnaba V, Barros-Martins J, Battistini L, Bauer W, Baumgart S, Baumgarth N, Baumjohann D, Baying B, Bebawy M, Becher B, Beisker W, Benes V, Beyaert R, Blanco A, Boardman DA, Bogdan C, Borger JG, Borsellino G, Boulais PE, Bradford JA, Brenner D, Brinkman RR, Brooks AES, Busch DH, Büscher M, Bushnell TP, Calzetti F, Cameron G, Cammarata I, Cao X, Cardell SL, Casola S, Cassatella MA, Cavani A, Celada A, Chatenoud L, Chattopadhyay PK, Chow S, Christakou E, Čičin-Šain L, Clerici M, Colombo FS, Cook L, Cooke A, Cooper AM, Corbett AJ, Cosma A, Cosmi L, Coulie PG, Cumano A, Cvetkovic L, Dang VD, Dang-Heine C, Davey MS, Davies D, De Biasi S, Del Zotto G, Dela Cruz GV, Delacher M, Della Bella S, Dellabona P, Deniz G, Dessing M, Di Santo JP, Diefenbach A, Dieli F, Dolf A, Dörner T, Dress RJ, Dudziak D, Dustin M, Dutertre CA, Ebner F, Eckle SBG, Edinger M, Eede P, Ehrhardt GRA, Eich M, Engel P, Engelhardt B, Erdei A, Esser C, Everts B, Evrard M, Falk CS, Fehniger TA, Felipo-Benaventura et al. Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition). Eur J Immunol. 2019 Oct;49(10):1457-1973. doi: 10.1002/eji.201970107.
  11. Hannemann N, Cao S, Eriksson D, Schnelzer A, Jordan J, Eberhardt M, Schleicher U, Rech J, Ramming A, Uebe S, Ekici A, Cañete JD, Chen X, Bäuerle T, Vera J, Bogdan C, Schett G, Bozec A. Transcription factor Fra-1 targets arginase-1 to enhance macrophage-mediated inflammation in arthritis.  J Clin Invest. 2019 Apr 16;129(7):2669-2684. doi: 10.1172/JCI96832.
  12. Abdissa K, Nerlich A, Beineke A, Ruangkiattikul N, Pawar V, Heise U, Janze N, Falk C, Bruder D, Schleicher U, Bogdan C, Weiss S, Goethe R. Presence of Infected Gr-1intCD11bhiCD11cint Monocytic Myeloid Derived Suppressor Cells Subverts T Cell Response and Is Associated With Impaired Dendritic Cell Function in Mycobacterium avium-Infected Mice. Front Immunol. 2018 Oct 16;9:2317. doi: 10.3389/fimmu.2018.02317. eCollection 2018.
  13. Straub T, Freudenberg MA, Schleicher U, Bogdan C, Gasteiger G, Pircher H. Bacterial coinfection restrains antiviral CD8 T-cell response via LPS-induced inhibitory NK cells. Nature Communications. 2018 Oct 8;9(1):4117. doi: 10.1038/s41467-018-06609-z.
  14. Naschberger E, Geißdörfer W, Bogdan C, Tripal P, Kremmer E, Stürzl M, Britzen-Laurent N. Processing and secretion of guanylate binding protein-1 depend on inflammatory caspase activity.  J Cell Mol Med. 2017 Sep;21(9):1954-1966. doi: 10.1111/jcmm.13116. Epub 2017 Mar 8.
  15. Hentschke I, Graser A, Melichar VO, Kiefer A, Zimmermann T, Kroß B, Haag P, Xepapadaki P, Papadopoulos NG, Bogdan C, Finotto S. IL-33/ST2 immune responses to respiratory bacteria in pediatric asthma. Sci Rep. 2017 Mar 6;7:43426. doi: 10.1038/srep43426.
  16. Sektioglu IM, Carretero R, Bender N, Bogdan C, Garbi N, Umansky V, Umansky L, Urban K, von Knebel-Döberitz M, Somasundaram V, Wink D, Beckhove P, Hämmerling GJ. Macrophage-derived nitric oxide initiates T-cell diapedesis and tumor rejection. Oncoimmunology. 2016 Aug 9;5(10):e1204506. doi: 10.1080/2162402X.2016.1204506. eCollection 2016.
  17. Brand A, Singer K, Koehl GE, Kolitzus M, Schoenhammer G, Thiel A, Matos C, Bruss C, Klobuch S, Peter K, Kastenberger M, Bogdan C, Schleicher U, Mackensen A, Ullrich E, Fichtner-Feigl S, Kesselring R, Mack M, Ritter U, Schmid M, Blank C, Dettmer K, Oefner PJ, Hoffmann P, Walenta S, Geissler EK, Pouyssegur J, Villunger A, Steven A, Seliger B, Schreml S, Haferkamp S, Kohl E, Karrer S, Berneburg M, Herr W, Mueller-Klieser W, Renner K, Kreutz M. LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells. Cell Metab. 2016 Nov 8;24(5):657-671. doi: 10.1016/j.cmet.2016.08.011. Epub 2016 Sep 15.
  18. Danzer C, Koller A, Baier J, Arnold H, Giessler C, Opoka R, Schmidt S, Willers M, Mihai S, Parsch H, Wirtz S, Daniel C, Reinhold A, Engelmann S, Kliche S, Bogdan C, Hoebe K, Mattner J. A mutation within the SH2 domain of slp-76 regulates the tissue distribution and cytokine production of iNKT cells in mice. Eur J Immunol. 2016 Sep;46(9):2121-36. doi: 10.1002/eji.201646331. Epub 2016 Jul 29.
  19. Schey R, Dornhoff H, Baier JL, Purtak M, Opoka R, Koller AK, Atreya R, Rau TT, Daniel C, Amann K, Bogdan C, Mattner J. CD101 inhibits the expansion of colitogenic T cells. Mucosal Immunol. 2016 Sep;9(5):1205-17. doi: 10.1038/mi.2015.139. Epub 2016 Jan 27.
  20. Siegert I, Schödel J, Nairz M, Schatz V, Dettmer K, Dick C, Kalucka J, Franke K, Ehrenschwender M, Schley G, Beneke A, Sutter J, Moll M, Hellerbrand C, Wielockx B, Katschinski DM, Lang R, Galy B, Hentze MW, Koivunen P, Oefner PJ, Bogdan C, Weiss G, Willam C, Jantsch J. Ferritin-Mediated Iron Sequestration Stabilizes Hypoxia-Inducible Factor-1α upon LPS Activation in the Presence of Ample Oxygen. Cell Rep. 2015 Dec 15;13(10):2048-55. doi: 10.1016/j.celrep.2015.11.005. Epub 2015 Nov 25.
  21. Christopoulos P, Dopfer EP, Malkovsky M, Esser PR, Schaefer HE, Marx A, Kock S, Rupp N, Lorenz MR, Schwarz K, Harder J, Martin SF, Werner M, Bogdan C, Schamel WW, Fisch P. A novel thymoma-associated immunodeficiency with increased naive T cells and reduced CD247 expression.  J Immunol. 2015 Apr 1;194(7):3045-53. doi: 10.4049/jimmunol.1402805. Epub 2015 Mar 2.
  22. Bogdan C, Steinkasserer A. Myeloid cells and the microenvironment, microorganisms and metabolism. Immunobiology. 2015 Feb;220(2):iii. doi: 10.1016/S0171-2985(14)00268-X.
  23. Siegert I, Schatz V, Prechtel AT, Steinkasserer A, Bogdan C, Jantsch J. Electroporation of siRNA into mouse bone marrow-derived macrophages and dendritic cells. Methods Mol Biol. 2014;1121:111-9. doi: 10.1007/978-1-4614-9632-8_9.

 

Vaccine research
  1. Niekrens V, Kunz B, Werner M, Valenza G, Seggewies C, Bogdan C, Esse J. Analysis of the effectiveness of hygiene measures and COVID-19 vaccination at a tertiary-care university hospital during the first two years of the SARS-CoV-2 pandemic.  Heliyon. 2024 Apr 26;10(9):e30311. doi: 10.1016/j.heliyon.2024.e30311. eCollection 2024 May 15
  2. Kocher K, Moosmann C, Drost F, Schülein C, Irrgang P, Steininger P, Zhong J, Träger J, Spriewald B, Bock C, Busch DH, Bogdan C, Schubert B, Winkler TH, Tenbusch M, Schuster EM, Schober K. Adaptive immune responses are larger and functionally preserved in a hypervaccinated individual. Lancet Infect Dis. 2024 May;24(5):e272-e274. doi: 10.1016/S1473-3099(24)00134-8. Epub 2024 Mar 4.
  3. Kling K, Domingo C, Bogdan C, Mertens T, Wolff R, Wiedermann U. Comment on: "New recommendation on yellow fever booster vaccination in Germany". Travel Med Infect Dis. 2023 Mar-Apr;52:102561. doi: 10.1016/j.tmaid.2023.102561. Epub 2023 Mar 24.
  4. Irrgang P, Gerling J, Kocher K, Lapuente D, Steininger P, Habenicht K, Wytopil M, Beileke S, Schäfer S, Zhong J, Ssebyatika G, Krey T, Falcone V, Schülein C, Peter AS, Nganou-Makamdop K, Hengel H, Held J, Bogdan C, Überla K, Schober K, Winkler TH, Tenbusch M. Class switch toward noninflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination. Sci Immunol. 2023 Jan 27;8(79):eade2798. doi: 10.1126/sciimmunol.ade2798. Epub 2023 Jan 27
  5. Kling K, Domingo C, Bogdan C, Wilder-Smith A, Harder T. Reply to Martin and Dauby. Clin Infect Dis. 2023 Apr 3;76(7):1344-1345. doi: 10.1093/cid/ciac891.
  6. Vogel E, Kocher K, Priller A, Cheng CC, Steininger P, Liao BH, Körber N, Willmann A, Irrgang P, Held J, Moosmann C, Schmidt V, Beileke S, Wytopil M, Heringer S, Bauer T, Brockhoff R, Jeske S, Mijocevic H, Christa C, Salmanton-García J, Tinnefeld K, Bogdan C, Yazici S, Knolle P, Cornely OA, Überla K, Protzer U, Schober K, Tenbusch M. Dynamics of humoral and cellular immune responses after homologous and heterologous SARS-CoV-2 vaccination with ChAdOx1 nCoV-19 and BNT162b2. EBioMedicine. 2022 Nov;85:104294. doi: 10.1016/j.ebiom.2022.104294. Epub 2022 Oct 4.
  7. Kling K, Domingo C, Bogdan C, Duffy S, Harder T, Howick J, Kleijnen J, McDermott K, Wichmann O, Wilder-Smith A, Wolff R. Duration of Protection After Vaccination Against Yellow Fever: A Systematic Review and Meta-Analysis. Clin Infect Dis. 2022 Dec 19;75(12):2266-2274. doi: 10.1093/cid/ciac580.
  8. Niekrens V, Esse J, Held J, Knobloch CS, Steininger P, Kunz B, Seggewies C, Bogdan C.Homologous COVID-19 BNT162b2 mRNA Vaccination at a German Tertiary Care University Hospital: A Survey-Based Analysis of Reactogenicity, Safety, and Inability to Work among Healthcare Workers. Vaccines (Basel). 2022 Apr 20;10(5):650. doi: 10.3390/vaccines10050650.
  9. Held J, Esse J, Tascilar K, Steininger P, Schober K, Irrgang P, Alsalameh R, Tenbusch M, Seggewies C, Bogdan C.Reactogenicity Correlates Only Weakly with Humoral Immunogenicity after COVID-19 Vaccination with BNT162b2 mRNA (Comirnaty®). Vaccines (Basel). 2021 Sep 24;9(10):1063. doi: 10.3390/vaccines9101063
  10. Tenbusch M, Schumacher S, Vogel E, Priller A, Held J, Steininger P, Beileke S, Irrgang P, Brockhoff R, Salmanton-García J, Tinnefeld K, Mijocevic H, Schober K, Bogdan C, Yazici S, Knolle P, Cornely OA, Überla K, Protzer U; DZIF-VACCELERATE-CoVaKo study team. Heterologous prime-boost vaccination with ChAdOx1 nCoV-19 and BNT162b2. Lancet Infect Dis. 2021 Sep;21(9):1212-1213. doi: 10.1016/S1473-3099(21)00420-5. Epub 2021 Jul 29.
  11. Bogdan C. STIKO vaccination recommendations : Vaccination of immunodeficient patients and vaccination against COVID-19. Hautarzt. 2021 Feb;72(2):92-99. doi: 10.1007/s00105-021-04761-0. Epub 2021 Jan 18.
  12. Laws HJ, Baumann U, Bogdan C, Burchard G, Christopeit M, Hecht J, Heininger U, Hilgendorf I, Kern W, Kling K, Kobbe G, Külper W, Lehrnbecher T, Meisel R, Simon A, Ullmann A, de Wit M, Zepp F. Impfen bei Immundefizienz : Anwendungshinweise zu den von der Ständigen Impfkommission empfohlenen Impfungen. (III) Impfen bei hämatologischen und onkologischen Erkrankungen (antineoplastische Therapie, Stammzelltransplantation), Organtransplantation und Asplenie. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2020 May;63(5):588-644. doi: 10.1007/s00103-020-03123-w.
  13. Vygen-Bonnet S, Hellenbrand W, Garbe E, von Kries R, Bogdan C, Heininger U, Röbl-Mathieu M, Harder T. Safety and effectiveness of acellular pertussis vaccination during pregnancy: a systematic review.  BMC Infect Dis. 2020 Feb 13;20(1):136. doi: 10.1186/s12879-020-4824-3.
  14. Wagner N, Assmus F, Arendt G, Baum E, Baumann U, Bogdan C, Burchard G, Föll D, Garbe E, Hecht J, Müller-Ladner U, Niehues T, Überla K, Vygen-Bonnet S, Weinke T, Wiese-Posselt M, Wojcinski M, Zepp F. Impfen bei Immundefizienz : Anwendungshinweise zu den von der Ständigen Impfkommission empfohlenen Impfungen. (IV) Impfen bei Autoimmunkrankheiten, bei anderen chronisch-entzündlichen Erkrankungen und unter immunmodulatorischer Therapie. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2019 Apr;62(4):494-515. doi: 10.1007/s00103-019-02905-1.
  15. Ehl S, Bogdan C, Niehues T, Burchard G, Baumann U, Hecht J, Koch J, Neubert J, Wiese-Posselt M, Zepp F. Impfen bei Immundefizienz: Anwendungshinweise zu den von der Ständigen Impfkommission empfohlenen Impfungen.(II) Impfen bei 1. Primären Immundefekterkrankungen und 2. HIV-Infektion. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2018 Aug;61(8):1034-1051. doi: 10.1007/s00103-018-2761-8.
  16. Niehues T, Bogdan C, Hecht J, Mertens T, Wiese-Posselt M, Zepp F. Impfen bei Immundefizienz : Anwendungshinweise zu den von der Ständigen Impfkommission empfohlenen Impfungen(I) Grundlagenpapier. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2017 Jun;60(6):674-684. doi: 10.1007/s00103-017-2555-4.
  17. Falkenhorst G, Remschmidt C, Harder T, Hummers-Pradier E, Wichmann O, Bogdan C.Effectiveness of the 23-Valent Pneumococcal Polysaccharide Vaccine (PPV23) against Pneumococcal Disease in the Elderly: Systematic Review and Meta-Analysis. PLoS One. 2017 Jan 6;12(1):e0169368. doi: 10.1371/journal.pone.0169368. eCollection 2017.
  18. Remschmidt C, Harder T, Wichmann O, Bogdan C, Falkenhorst G. Effectiveness, immunogenicity and safety of 23-valent pneumococcal polysaccharide vaccine revaccinations in the elderly: a systematic review.  BMC Infect Dis. 2016 Nov 25;16(1):711. doi: 10.1186/s12879-016-2040-y.
  19. Falkenhorst G, Remschmidt C, Harder T, Wichmann O, Glodny S, Hummers-Pradier E, Ledig T, Bogdan C.Background paper to the updated pneumococcal vaccination recommendation for older adults in Germany. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2016 Dec;59(12):1623-1657. doi: 10.1007/s00103-016-2466-9.
  20. Weinberger R, Falkenhorst G, Bogdan C, van der Linden M, Imöhl M, von Kries R. Incidence of invasive pneumococcal disease in 5-15 year old children with and without comorbidities in Germany after the introduction of PCV13: Implications for vaccinating children with comorbidities. Vaccine. 2015 Nov 27;33(48):6617-21. doi: 10.1016/j.vaccine.2015.10.102. Epub 2015 Nov 1.
  21. Hellenbrand W, Koch J, Harder T, Bogdan C, Heininger U, Tenenbaum T, Terhardt M, Vogel U, Wichmann O, von Kries R. Background Paper for the update of meningococcal vaccination recommendations in Germany: use of the serogroup B vaccine in persons at increased risk for meningococcal disease. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2015 Nov;58(11-12):1314-43. doi: 10.1007/s00103-015-2253-z.

 

Clinical microbiology, microbiological diagnostics, hospital hygiene, epidemiology
  1. Valenza G, Eisenberger D, Voigtländer S, Alsalameh R, Gerlach R, Koch S, Kunz B, Held J, Bogdan C.  Emergence of novel ST1299 vanA lineages as possible cause for the striking rise of vancomycin resistance among invasive strains of Enterococcus faecium at a German university hospital. Microbiol Spectr. 2023 Dec 12;11(6):e0296223. doi: 10.1128/spectrum.02962-23. Epub 2023 Oct 31.
  2. Erb T, Mihai S, Strauß R, Herbst L, Castellanos I, Diesch K, Cipa F, Bihlmaier K, Lang A-K, Ganslmayer M, Willam C, Bremer F, Fürst J, Beyer C, Bogdan C, Rath A, Held J.  β-(1→3)-D-glucan- and mannan-guided early termination of antifungal therapy in ICU patients: a randomized controlled study. Antimicrob Agents Chemother. 2023 Nov 15;67(11):e0072523. doi: 10.1128/aac.00725-23. Epub 2023 Oct 12
  3. Esse J, Träger J, Valenza G, Bogdan C, Held J. Rapid phenotypic antimicrobial susceptibility testing of Gram-negative rods directly from positive blood cultures using the novel Q-linea ASTar system. J Clin Microbiol. 2023 Nov 21;61(11):e0054923. doi: 10.1128/jcm.00549-23. Epub 2023 Oct 11
  4. Halamicek R, Wiesmann C, Kröner R, Eber M, Bogdan C, Schubert DW. Influence of different treatment conditions on the filtration performance of conventional electret melt blown non-woven and novel nano FFP2 masks. PLoS One. 2023 Sep 21;18(9):e0291679. doi: 10.1371/journal.pone.0291679. eCollection 2023
  5. Seidel CL, Strobel K, Weider M, Tschaftari M, Unertl C, Willershausen I, Weber M, Hoerning A, Morhart P, Schneider M, Beckmann MW, Bogdan C, Gerlach RG, Gölz L. Orofacial clefts alter early life oral microbiome maturation towards higher levels of potentially pathogenic species: A prospective observational study. J Oral Microbiol. 2023 Jan 4;15(1):2164147. doi: 10.1080/20002297.2022.2164147. eCollection 2023.
  6. Friedrich B, Eichermüller J, Bogdan C, Cunningham S, Hackstein H, Strauß R, Alexiou C, Lyer S, Tietze R. Biomimetic Magnetic Particles for the Removal of Gram-Positive Bacteria and Lipoteichoic Acid. Pharmaceutics. 2022 Oct 31;14(11):2356. doi: 10.3390/pharmaceutics14112356.
  7. Seidel CL, Gerlach RG, Weider M, Wölfel T, Schwarz V, Ströbel A, Schmetzer H, Bogdan C, Gölz L. Influence of probiotics on the periodontium, the oral microbiota and the immune response during orthodontic treatment in adolescent and adult patients (ProMB Trial): study protocol for a prospective, double-blind, controlled, randomized clinical trial. BMC Oral Health. 2022 Apr 27;22(1):148. doi: 10.1186/s12903-022-02180-8.
  8. Friedrich B, Lyer S, Janko C, Unterweger H, Brox R, Cunningham S, Dutz S, Taccardi N, Bikker FJ, Hurle K, Sebald H, Lenz M, Spiecker E, Fester L, Hackstein H, Strauß R, Boccaccini AR, Bogdan C, Alexiou C, Tietze R. Scavenging of bacteria or bacterial products by magnetic particles functionalized with a broad-spectrum pathogen recognition receptor motif offers diagnostic and therapeutic applications. Acta Biomater. 2022 Mar 15;141:418-428. doi: 10.1016/j.actbio.2022.01.001. Epub 2022 Jan 7.
  9. Huber T, Steininger P, Irrgang P, Korn K, Tenbusch M, Diesch K, Achenbach S, Kremer AE, Werblow M, Vetter M, Bogdan C, Held J. Diagnostic performance of four SARS-CoV-2 antibody assays in patients with COVID-19 or with bacterial and non-SARS-CoV-2 viral respiratory infections. Eur J Clin Microbiol Infect Dis. 2021 Sep;40(9):1983-1997. doi: 10.1007/s10096-021-04285-4. Epub 2021 Jun 9.
  10. Seidel CL, Gerlach RG, Wiedemann P, Weider M, Rodrian G, Hader M, Frey B, Gaipl US, Bozec A, Cieplik F, Kirschneck C, Bogdan C, Gölz L. Defining Metaniches in the Oral Cavity According to Their Microbial Composition and Cytokine Profile. Int J Mol Sci. 2020 Nov 3;21(21):8218. doi: 10.3390/ijms21218218.
  11. Huber T, Serr A, Geißdörfer W, Hess C, Lynker-Aßmus C, von Loewenich FD, Bogdan C, Held J. Evaluation of the Amplex eazyplex Loop-Mediated Isothermal Amplification Assay for Rapid Diagnosis of Pneumocystis jirovecii Pneumonia. J Clin Microbiol. 2020 Nov 18;58(12):e01739-20. doi: 10.1128/JCM.01739-20. Print 2020 Nov 18
  12. Ziegler K, Rath A, Schoerner C, Meyer R, Bertsch T, Erbguth F, Bogdan C, Steinmann J, Held J. Comparative Analysis of the Euroimmun CXCL13 Enzyme-Linked Immunosorbent Assay and the ReaScan Lateral Flow Immunoassay for Diagnosis of Lyme Neuroborreliosis. J Clin Microbiol. 2020 Aug 24;58(9):e00207-20. doi: 10.1128/JCM.00207-20. Print 2020 Aug 24.
  13. Eisenberger D, Tuschak C, Werner M, Bogdan C, Bollinger T, Hossain H, Friedrich P, Hussein Z, Pöhlmann C, Würstl B, Nickel S, Lehner-Reindl V, Höller C, Liebl B, Valenza G. Whole-genome analysis of vancomycin-resistant Enterococcus faecium causing nosocomial outbreaks suggests the occurrence of few endemic clonal lineages in Bavaria, Germany. J Antimicrob Chemother. 2020 Jun 1;75(6):1398-1404. doi: 10.1093/jac/dkaa041.
  14. Horch RE, Krappmann S, Dümig M, Schmitz M, Kengelbach-Weigand A, Schubert DW, Kremser T, Bogdan C, Ludolph I. Aspergillus fumigatus Spores Are Not Able to Penetrate Silicone Breast Implant Shells. Ann Plast Surg. 2020 Sep;85(3):306-309. doi: 10.1097/SAP.0000000000002135.
  15. Valenza G, Werner M, Eisenberger D, Nickel S, Lehner-Reindl V, Höller C, Bogdan C.First report of the new emerging global clone ST1193 among clinical isolates of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli from Germany.  J Glob Antimicrob Resist. 2019 Jun;17:305-308. doi: 10.1016/j.jgar.2019.01.014. Epub 2019 Jan 22.
  16. Karawacka W, Janko C, Unterweger H, Mühlberger M, Lyer S, Taccardi N, Mokhir A, Jira W, Peukert W, Boccaccini AR, Kolot M, Strauss R, Bogdan C, Alexiou C, Tietze R. SPIONs functionalized with small peptides for binding of lipopolysaccharide, a pathophysiologically relevant microbial product. Colloids Surf B Biointerfaces. 2019 Feb 1;174:95-102. doi: 10.1016/j.colsurfb.2018.11.002. Epub 2018
  17. Wolff D, Feldt T, Reifenberger J, Sebald H, Bogdan C.Closing the Brief Case: Cutaneous Sporotrichosis in an Immunocompetent Patient after Travel to Peru. J Clin Microbiol. 2018 Oct 25;56(11):e01961-17. doi: 10.1128/JCM.01961-17. Print 2018 Nov.
  18. Wolff D, Feldt T, Reifenberger J, Sebald H, Bogdan C.The Brief Case: Cutaneous Sporotrichosis in an Immunocompetent Patient after Travel to Peru. J Clin Microbiol. 2018 Oct 25;56(11):e01958-17. doi: 10.1128/JCM.01958-17. Print 2018 Nov.
  19. Friedrich R, Rappold E, Bogdan C, Held J. Comparative Analysis of the Wako β-Glucan Test and the Fungitell Assay for Diagnosis of Candidemia and Pneumocystis jirovecii Pneumonia. J Clin Microbiol. 2018 Aug 27;56(9):e00464-18. doi: 10.1128/JCM.00464-18. Print 2018 Sep.
  20. Steininger PA, Bobinger T, Dietrich W, Lee DH, Knott M, Bogdan C, Korn K, Lang R. Two Cases of Severe Tick-Borne Encephalitis in Rituximab-Treated Patients in Germany: Implications for Diagnosis and Prevention. Open Forum Infect Dis. 2017 Sep 26;4(4):ofx204. doi: 10.1093/ofid/ofx204. eCollection 2017 Fall.
  21. Träger J, Melichar VO, Meyer R, Rauh M, Bogdan C, Held J. Serum (1→3)-β-D-glucan and galactomannan levels in patients with cystic fibrosis: a retrospective cohort study. BMC Pulm Med. 2018 Mar 27;18(1):52. doi: 10.1186/s12890-018-0614-8.
  22. Heckel M, Stiel S, Herbst FA, Tiedtke JM, Sturm A, Adelhardt T, Bogdan C, Sieber C, Schöffski O, Lang FR, Ostgathe C. Multidrug-resistant bacterial microorganisms (MDRO) in end-of-life care: development of recommendations for hospitalized patients using a mixed-methods approach. Support Care Cancer. 2018 Sep;26(9):3021-3027. doi: 10.1007/s00520-018-4149-6. Epub 2018 Mar 16.
  23. Sunderkötter C, Becker K, Kutzner H, Meyer T, Blödorn-Schlicht N, Reischl U, Nenoff P, Geißdörfer W, Gräser Y, Herrmann M, Kühn J, Bogdan C. Molecular diagnosis of skin infections using paraffin-embedded tissue - review and interdisciplinary consensus.  J Dtsch Dermatol Ges. 2018 Feb;16(2):139-147. doi: 10.1111/ddg.13438.
  24. Kiefer A, Bogdan C, Melichar VO. Successful eradication of newly acquired MRSA in six of seven patients with cystic fibrosis applying a short-term local and systemic antibiotic scheme. BMC Pulm Med. 2018 Jan 25;18(1):20. doi: 10.1186/s12890-018-0588-6.
  25. Heckel M, Geißdörfer W, Herbst FA, Stiel S, Ostgathe C, Bogdan C.Nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) at a palliative care unit: A prospective single service analysis.  PLoS One. 2017 Dec 11;12(12):e0188940. doi: 10.1371/journal.pone.0188940. eCollection 2017.
  26. Winterholler M, Coras R, Geißdörfer W, Rammensee R, Gölitz P, Bogdan C, Lang R. Fatal Mycotic Aneurysm of the Basilar Artery Caused by Aspergillus fumigatus in a Patient with Pituitary Adenoma and Meningitis. Front Med (Lausanne). 2017 Jul 18;4:113. doi: 10.3389/fmed.2017.00113. eCollection 2017.
  27. Wons J, Meiller R, Bergua A, Bogdan C, Geißdörfer W. Follicular Conjunctivitis due to Chlamydia felis-Case Report, Review of the Literature and Improved Molecular Diagnostics. Front Med (Lausanne). 2017 Jul 17;4:105. doi: 10.3389/fmed.2017.00105. eCollection 2017.
  28. Glaser C, Rieg S, Wiech T, Scholz C, Endres D, Stich O, Hasselblatt P, Geißdörfer W, Bogdan C, Serr A, Häcker G, Voll RE, Thiel J, Venhoff N. Whipple's disease mimicking rheumatoid arthritis can cause misdiagnosis and treatment failure. Orphanet J Rare Dis. 2017 May 25;12(1):99. doi: 10.1186/s13023-017-0630-4.
  29. Hammer A, Wolff D, Geißdörfer W, Schrey M, Ziegler R, Steiner HH, Bogdan C.A spinal epidural abscess due to Streptobacillus moniliformis infection following a rat bite: case report. J Neurosurg Spine. 2017 Jul;27(1):92-96. doi: 10.3171/2016.12.SPINE161042. Epub 2017 Apr 21.
  30. Grankvist A, Moore ER, Svensson Stadler L, Pekova S, Bogdan C, Geißdörfer W, Grip-Lindén J, Brandström K, Marsal J, Andréasson K, Lewerin C, Welinder-Olsson C, Wennerås C. Multilocus Sequence Analysis of Clinical "Candidatus Neoehrlichia mikurensis" Strains from Europe. J Clin Microbiol. 2015 Oct;53(10):3126-32. doi: 10.1128/JCM.00880-15. Epub 2015 Jul 8.
  31. Frobenius W, Bogdan C.Diagnostic Value of Vaginal Discharge, Wet Mount and Vaginal pH - An Update on the Basics of Gynecologic Infectiology. Geburtshilfe Frauenheilkd. 2015 Apr;75(4):355-366. doi: 10.1055/s-0035-1545909.
  32. Stanger KM, Albert F, Kneser U, Bogdan C, Horch RE. Management of chronic osteomyelitis of the tibia with life-threatening complications under negative pressure wound therapy and isolation of Helcococcus kunzii. Int Wound J. 2015 Aug;12(4):443-6. doi: 10.1111/iwj.12133. Epub 2013 Jul 16.
  33. Hammon M, Kunz B, Dinzl V, Kammerer FJ, Schwab SA, Bogdan C, Uder M, Schlechtweg PM. Practicability of hygienic wrapping of touchscreen operated mobile devices in a clinical setting. PLoS One. 2014 Sep 2;9(9):e106445. doi: 10.1371/journal.pone.0106445. eCollection 2014.
  34. Wennerås C, Bloemberg G, Bogdan C. Reply to Raoult.  Clin Infect Dis. 2014 Oct;59(7):1042-3. doi: 10.1093/cid/ciu494. Epub 2014 Jun 25.
  35. Grankvist A, Andersson PO, Mattsson M, Sender M, Vaht K, Höper L, Sakiniene E, Trysberg E, Stenson M, Fehr J, Pekova S, Bogdan C, Bloemberg G, Wennerås C. Infections with the tick-borne bacterium "Candidatus Neoehrlichia mikurensis" mimic noninfectious conditions in patients with B cell malignancies or autoimmune diseases. Clin Infect Dis. 2014 Jun;58(12):1716-22. doi: 10.1093/cid/ciu189. Epub 2014 Mar 18.

 

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