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Publications

Publications

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  • Seidel C. L., Gerlach R.G., Wieder M., Wölfel T., Schwarz V., Ströbel A., Schmetzer H., Bogdan C. and Gölz L. (2022) Influence of probiotics on the periodontium, the oral microbiota and the immune response during orthodontic treatment in adolescent and adult patients (ProMB Trial): study protocol for a prospective, double-blind, controlled, randomized clinical trial. BMC Oral Health, 22(1):148, doi: 10.1186/s12903-022-02180-8.
  • Koeppel M. B., Glaser J., Baumgartner T., Spriewald S., Gerlach R. G., von Armansperg B., Leong J. M. and Stecher B. (2021) Scalable Reporter Assays to Analyze the Regulation of stx2 Expression in Shiga Toxin-Producing Enteropathogens. Toxins, 13(8):534, doi: 10.3390/toxins13080534. Editor’s Choice in volume 13, issue 8 of Toxins
  • Seidel C. L., Gerlach R. G., Wiedemann P., Weider M., Rodrian G., Hader, M., Frey B., Gaipl U., Bozec A., Cieplik F., Kirschneck C., Bogdan C. and Gölz L. (2020) Defining Metaniches in the Oral Cavity According to Their Microbial Composition and Cytokine Profile. International Journal of Molecular Sciences, 21(21):8218, doi: 10.3390/ijms21218218.
  • Klingl S., Kordes S., Schmid B., Gerlach R. G., Hensel M. and Muller Y. A. (2020) Recombinant protein production and purification of SiiD, SiiE and SiiF - components of the SPI4-encoded type I secretion system from Salmonella Typhimurium. Protein Expression and Purification, 3:105632, doi: 10.1016/j.pep.2020.105632.
  • Kapach G., Nuri R., Schmidt C., Danin A., Ferrera S., Savidor A., Gerlach R.G. and Shai Y. (2020) Loss of the periplasmic chaperone Skp and mutations in the efflux pump AcrAB-TolC play a role in acquired resistance to antimicrobial peptides in Salmonella Typhimurium. Frontiers in Microbiology, 11:189, doi: 10.3389/fmicb.2020.00189.
  • Kirchweger P., Weiler S., Egerer-Sieber C., Blasl A.T., Hoffmann S., Schmidt C., Sander N., Merker D., Gerlach R.G., Hensel M. and Muller Y.A. (2019) Structural and functional characterization of SiiA, an auxiliary protein from the SPI4-encoded type 1 secretion system from Salmonella Typhimurium. Molecular Microbiology, 112(5):1403-1422.
  • Herp S., Brugiroux S., Garzetti D., Ring D., Jochum L.M., Beutler M., Eberl C., Hussain S., Walter S., Gerlach R.G., Ruscheweyh H.J., Huson D., Sellin M.E., Slack E., Hanson B., Loy A., Baines J.F., Rausch P., Basic M., Bleich A., Berry D. and Stecher B. (2019) Mucispirillum schaedleri Antagonizes Salmonella Virulence to Protect Mice against Colitis. Cell Host & Microbe, 25:1–14.
  • Neubert P., Weichselbaum A., Reitinger C., Schatz V., Schröder A., Ferdinand J.R., Simon M., Bär A.L., Brochhausen C., Gerlach R.G., Tomiuk S., Hammer K., Wagner S., van Zandbergen G., Binger K.J., Müller D.N., Kitada K., Clatworthy M.R., Kurts C., Titze J., Abdullah Z. and Jantsch J. (2019) HIF1A and NFAT5 coordinate Na+-boosted antibacterial defense via enhanced autophagy and autolysosomal targeting. Autophagy, 15(11):1899-1916
  • Hoffmann S., Walter S., Blume A.K., Fuchs S., Schmidt C., Scholz A. and Gerlach R.G. (2018) High-throughput quantification of bacterial-cell interactions using virtual colony counts. Frontiers in Cellular and Infection Microbiology, 8:43.
  • Gerlach R.G., Walter S., McClelland M., Schmidt C., Steglich M., Prager R., Bender J.K., Fuchs S., Schoerner C., Rabsch W., Lang W. and Jantsch J. (2017) Comparative whole genome analysis of three consecutive Salmonella diarizonae isolates. International Journal of Medical Microbiology,307(8):542-551.
  • Wilck N., Matus M.G., Kearney S.M., Olesen S.W., Forsland K., Bartolomaeus H., Haase S., Mähler A., Balogh A., Markó L., Vvedenskaya O., Kleiner F.H., Tsvetkov D., Klug L., Costea P.I., Sunagawa S., Maier L., Rakova N., Schatz V., Neubert P., Frätzer C., Krannich A., Gollasch M., Grohme D.A., Côrte-Real B.F., Gerlach R.G., Basic M., Typas A., Wu C., Titze J.M., Jantsch J., Boschmann M., Dechend R., Kleinewietfeld M., Kempa S., Bork P., Linker R.A., Alm E.J. and Müller D.N. (2017) Salt-responsive gut commensal modulates TH17 axis and disease. Nature, 551(7682):585-589.
  • Peters B., Stein J., Klingl S., Sander N., Sandmann A., Taccardi N., Sticht H., Gerlach R.G., Muller Y.A. and Hensel M. (2017) Structural and functional dissection reveals distinct roles of Ca2+-binding sites in the giant adhesin SiiE of Salmonella enterica. PLoS Pathogens, 13(5):e1006418.
  • Hoffmann S., Schmidt C., Walter S., Bender J.K. and Gerlach R.G. (2017) Scarless deletion of up to seven methyl-accepting chemotaxis genes with an optimized method highlights key function of CheM in Salmonella Typhimurium. PLoS One, 12(2):e0172630.
  • Simon M., Melzl H., Hiergeist A., Richert K., Falgenhauer L., Pfeifer Y., Gerlach R.G., Fuchs K., Reischl U., Gessner A. and Jantsch J. (2017) Colistin- and carbapenem-resistant Klebsiella oxytoca harboring blaVIM-2 and an insertion in the mgrB gene isolated from blood culture. International Journal of Medical Microbiology, 307(2):113-5.
  • Nedialkova L.P., Sidstedt M., Koeppel M.B., Spriewald S., Ring D., Gerlach R.G., Bossi L. and Stecher B. (2016) Temperate phages promote colicin-dependent fitness of Salmonella enterica serovar Typhimurium. Environmental Microbiology,18(5):1591-603.
  • Jennewein, J., Matuszak, J., Walter, S., Felmy, B., Gendera, K., Schatz, V., Nowottny, M., Liebsch, G., Hensel, M., Hardt, W.D., Gerlach, R.G.* and Jantsch*, J. (2015) Low-oxygen tensions found in Salmonella-infected gut tissue boost Salmonella replication in macrophages by impairing antimicrobial activity and augmenting Salmonella virulence. Cellular Microbiology, 17(12):1833-47. (*shared correspondence)
  • Bielecki, P., Jensen, V., Schulze, W., Gödeke, J., Strehmel, J., Eckweiler, D., Nicolai, T., Bielecka, A., Wille, T., Gerlach, R.G., and Häussler, S. (2015) Cross talk between the response regulators PhoB and TctD allows for the integration of diverse environmental signals in Pseudomonas aeruginosa. Nucleic Acids Research, Jul;43(13):6413-25.
  • Wille, T., Barlag, B., Jakovljevic, V., Hensel, M., Sourjik, V. and Gerlach, R.G. (2015). A Gateway-based system for fast evaluation of protein-protein interactions in bacteria. PLoS One, Apr;10(4):e0123646.
  • Fischer, M., Zilkenat, S., Gerlach, R.G., Wagner, S. and Renard, B.Y. (2014) Pre- and post-processing workflow for affinity purification mass spectrometry data. Journal of Proteome Research, May;13(5):2239-49.
  • Wagner, C., Barlag, B., Gerlach, R.G., Deiwick, J. and Hensel, M. (2014) The giant adhesin SiiE binds to polarized epithelial cells in a lectin-like manner. Cellular Microbiology, Jun;16(6):962-75.
  • Nedialkova, L., Denzler, R., Koeppel, M.B., Diehl, M., Ring, D., Wille, T., Gerlach, R.G. and Stecher, B. (2014) Inflammation triggers ColIb-dependent competition of Salmonella serovar Typhimurium and colicin-sensitive E. coli in Enterobacterial blooms. PLoS Pathogens, 10(1):e1003844
  • Wille, T., Wagner, C., Mittelstädt, W., Blank, K., Sommer, E., Malengo, G., Döhler, D., Lange, A., Sourjik, V., Hensel, M. and Gerlach, R.G. (2014) SiiA and SiiB are novel type I secretion system subunits controlling SPI4-mediated adhesion of Salmonella enterica.Cellular Microbiology, Feb;16(2):161-78. Editor’s Choice in issue 02/2014 of Cellular Microbiology
  • Bender, J.K., Wille, T., Blank, K., Lange, A. and Gerlach, R.G. (2013). LPS structure and PhoQ activity are important for Salmonella Typhimurium virulence in the Galleria mellonella infection model. PLoS One 8, e73287.
  • Jantsch, J., Gerlach, R.G., Ensser, A., Dahesh, S., Popp, I., Heeg, C., Bleiziffer, O., Merz, T., Schulz, T., Horch, R., Bogdan, C., Nizet, V. and van der Linden, M. (2013). Severe soft tissue infection caused by a non-β-hemolytic Streptococcus pyogenes strain harboring a premature stop mutation in the sagC gene. Journal of Clinical Microbiology, 51(6):1962-5.
  • Wiese, M., Gerlach R.G., Popp I., Matuszak J., Mahapatro M., Castiglione K., Chakravortty D., Willam C., Hensel M., Bogdan C. and Jantsch J. (2012). Hypoxia-mediated impairment of the mitochondrial respiratory chain inhibits the bactericidal activity of macrophages. Infection and Immunity, 80(4):1455-66.
  • Wille, T., Blank, K., Schmidt, C., Vogt, V. and Gerlach, R.G. (2012). Gaussia princeps Luciferase as a Reporter for Transcriptional Activity, Protein Secretion, and Protein-Protein Interactions in Salmonella enterica Serovar Typhimurium. Applied and Environmental Microbiology, 78(1):250-7.
  • Wagner, C., Polke, M., Gerlach, R.G., Linke, D., Stierhof, Y.D., Schwarz, H. and Hensel, M. (2011) Functional dissection of SiiE, a giant non-fimbrial adhesin of Salmonella enterica. Cellular Microbiology, 13(8):1286-301.
  • Blank, K., Hensel, M. and Gerlach, R.G. (2011). Rapid and Highly Efficient Method for Scarless Mutagenesis within the Salmonella enterica Chromosome. PLoS One 6, e15763.
  • Ott, L., Höller, M., Gerlach, R.G., Hensel, M., Rheinlaender, J., Schäffer, T.E. and Burkovski, A. (2010) Corynebacterium diphtheriae invasion-associated protein (DIP1281) is involved in cell surface organization, adhesion and internalization in epithelial cells. BMC Microbiology, (10):2.
  • Gerlach, R.G., Jäckel, D., Hölzer, S.U. and Hensel, M. (2009) Rapid oligonucleotide-based recombineering of the chromosome of Salmonella enterica. Applied and Environmental Microbiology, 75(6):1575-80.
  • Gerlach, R.G., Cláudio, N., Rohde, M., Jäckel, D., Wagner, C. and Hensel, M. (2008), Cooperation of Salmonella Pathogenicity Islands 1 and 4 Is Required To Breach Epithelial Barriers. Cellular Microbiology, 10(11):2364-76.
  • Jantsch, J., Chakravortty, D., Turza, N., Prechtel., A.T., Buchholz, B., Gerlach, R.G., Volke, M., Gläsner, J., Warnecke, C., Wiesener, M.S., Eckardt, K.U., Steinkasserer, A., Hensel, M. and Willam, C. (2008) Hypoxia and hypoxia-inducible factor-1α modulate lipopolysaccharide-induced dendritic cell activation and function. Journal of Immunology, 180(7):4697-705.
  • Gerlach, R.G., Jäckel, D., Stecher, B., Wagner, C., Lupas, A., Hardt W.-D. and Hensel, M. (2007) Salmonella Pathogenicity Island 4 Encodes A Giant Non-fimbrial Adhesin and The Cognate Type I Secretion System. Cellular Microbiology, 9(7):1834-50.
  • Gerlach, R.G., Jäckel, D., Geymeier, N. and Hensel, M. (2007), Salmonella Pathogenicity Island 4-mediated Adhesion Is Co-regulated With Invasion Genes In Salmonella enterica. Infection and Immunity, 75(10):4697-709.
  • Gerlach, R.G., Hölzer, S.U., Jäckel, D. and Hensel, M. (2007), Rapid engineering of bacterial reporter gene fusions using Red recombination. Applied Environmental Microbiology, 73(13):4234-42.
  • Westermann, M., Pop, O.I., Gerlach, R., Appel, T.R., Schlormann, W., Schreiber, S. and Müller, J.P. (2006) The TatAd component of the Bacillussubtilis twin-arginine protein transport system forms homo-multimeric complexes in its cytosolic and membrane embedded localisation. Biochimica et biophysica acta - Biomembranes, 1758 (4):443-51.
  • Gerlach, R., Pop, O. and Müller, J.P. (2004) Tat dependent export of E. coli phytase AppA by using the PhoD-specific transport system of Bacillus subtilis. Journal of Basic Microbiology, 44(5):351-9.
  • Pop, O.I., Westermann, M., Volkmer-Engert, R., Schulz, D., Lemke, C., Schreiber, S., Gerlach, R., Wetzker, R. and Müller, J.P. (2003) Sequence-specific binding of prePhoD to soluble TatAd indicates protein-mediated targeting of the Tat export in Bacillussubtilis. The Journal of Biological Chemistry, 278(40):38428-36
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