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Publications

Publications

  1. Hawerkamp HC, Fahy CMR, Fallon PG, Schwartz C. Break on through: The role of innate immunity and barrier defence in atopic dermatitis and psoriasis. Skin Health Dis. 2022; e99
  2. Schwartz C, Fallon PG. Determining Coreceptor Expression and Function in Murine ILC2 Through Flow Cytometry Characterization and Coculture Techniques. Methods Mol Biol. 2020; 212:71-82.
  3. Schwartz C, Voehringer D. Identification of Murine Basophils by Flow Cytometry and Histology. Methods Mol Biol. 2020; 2163:367-375.
  4. Saunders SP, Floudas A, Moran T, Byrne CM, Rooney MD, Fahy CMR, Geoghegan JA, Iwakura Y, Fallon PG, Schwartz C. Dysregulated skin barrier function in Tmem79 mutant mice promotes IL-17A-dependent spontaneous skin and lung inflammation. Allergy. 2020 Dec; 75(12): 3216-3227.
  5. Fallon PG, Schwartz C. The high and lows of type 2 asthma and mouse models. J Allergy Clin Immunol. 2020 Feb; 145(2):496-498.
  6. Floudas A, Aviello G, Schwartz C, Jeffery IB, O’Toole PW, Fallon PG. Schistosoma mansoni Worm Infection Regulates the Intestinal Microbiota and Susceptibility to Colitis. Infect Immun. 2019 Jul 23; 87(8):e00275-19.
  7. Schwartz C, Moran T, Saunders SP, Kaszlikowska A, Floudas A, Bom J, Nunez G, Iwakura Y, O’Neill LAJ, Irvine AD, McKenzie ANJ, Ogg G, Walsh PT, Demengeot, Fallon PG. Spontaneous atopic dermatitis in mice with a defective skin barrier is independent of ILC2 and mediated by IL-1β. Allergy. 2019 Apr 2. doi: 10.1111/all.13801.
  8. Schwartz C, Fallon PG. Schistosoma “Eggs-Iting” the Host: Granuloma Formation and Egg Excretion. Front Immunol. 2018 Oct 29; 9: 2492.
  9. Schwartz C, Hams E, Fallon PG. Helminth Modulation of Lung Inflammation. Trends Parasitol. 2018 Jan 12. pii: S1471-4922(17)30312-4.
  10. Schwartz C, Khan AR, Floudas A, Saunders SP, Hams E, Rodewald HR, McKenzie AN, Fallon PG. ILC2 regulate adaptive Th2 functions via PD-L1 checkpoint control. J Exp Med. 2017 Sept 4; 214(9):2507-2521.
  11. Minutti CM, Drube S, Blair N, Schwartz C, McCrae JC, McKenzie AN, Kamradt T, Mokry M, Coffer PJ, Sibilia M, Sijts AJ, Fallon PG, Maizels RM, Zaiss DM. Epidermal growth factor receptor expression licenses Th2 cells to function in a TCRindependent way. Immunity. 2017. Oct 17;47(4):710-722.e6.
  12. Floudas A, Saunders SP, Moran T, Schwartz C, Hams E, Fitzgerald DC, Johnston JA, Amagai M, Ogg GS, McKenzie AN, Walsh PT, Fallon PG. Interleukin-17 receptor A maintains and protects the skin barrier to prevent allergic skin inflammation. J Immunol. 2017 Jul 15; 199(2):707-717.
  13. Schwartz C, Eberle JU, Hoyler T, Diefenbach A, Lechmann M, Voehringer D. Opposing functions of TSLP-responsive basophils and dendritic cells in a mouse model of atopic dermatitis. J Allergy Clin Immunol. 2016 Nov; 138(5):1443-46.
  14. Schwartz C, O’Grady K, Lavelle EC, Fallon PG. Interleukin 33: an innate alarm for adaptive responses beyond Th2 immunity – emerging roles in obesity, intestinal inflammation, and cancer. Eur J Immunol. 2016 May; 46(5):1091-100.
  15. Schwartz C, Eberle JU, Voehringer D. Basophils in inflammation. Eur J Pharmacol. 2016 May 5; 778:90-5.
  16. Geurts N, Vangansewinkel T, Lemmens S, Nelissen S, Geboes L, Schwartz C, Voehringer D, Hendrix S. Basophils are dispensable for the recovery of gross locomotion after spinal chord hemisection injury. J Leukoc Biol. 2016 Apr; 99(4):579-82.
  17. Turqueti-Neves A, Otte M, Schwartz C, Schmitt MER, Lindner C, Pabst O, Yu P, Voehringer D. The extracellular domains of IgG1 and T cell-derived IL-4/IL-13 are critical for the polyclonal memory IgE response in vivo. PLoS Biol. 2015 Nov 2; 13(11):e1002290.
  18. Binger KJ, Gebhardt M, Heinig M, Rintisch C, Schroeder A, Neuhofer W, Hilgers K, Manzel A, Schwartz C, Kleinewietfeld M, Linker RA, Lang F, Voehringer D, Wright MD, Hubner N, Dechend R, Jantsch J, Teitze J, Muller DN. High salt reduces the activation of IL-4+IL-13 stimulated macrophages. J Clin Invest. 2015 Nov 2; 125(11):4223-38.
  19. Schwartz C, Willebrand R, Huber S, Rupec RA, Wu D, Locksley R, Voehringer D. Eosinophil-specific deletion of IκBα in mice reveals a critical role of NF-κB-induced Bcl-xL for inhibition of apoptosis. Blood. 2015 Jun 18;125(25):3896-904.
  20. Hewitson JP, Filbey KJ, Esser-von Bieren J, Camberis M, Schwartz C, Murray J, Reynolds LA, Blair N, Robertson E, Harcus Y, Boon L, Huang SC, Yang L, Tu Y, Miller MJ, Voehringer D, Le Gros G, Harris N, Maizels RM. Concerted activity of IgG1 antibodies and IL-4/IL-25-dependent effector cells trap helminth larvae in the tissues following vaccination with defined secreted antigens, providing sterile immunity to challenge infection. PLoS Pathog. 2015 Mar 27;11(3):e1004676.
  21. Schwartz C, Turqueti-Neves A, Hartmann S, Yu P, Nimmerjahn F, Voehringer D. Basophil-mediated protection against gastrointestinal helminths requires IgE-induced cytokine secretion. Proc Natl Acad Sci U S A. 2014 Dec 2; 111(48):E5169-77.
  22. Oeser K, Schwartz C, Voehringer D. Conditional IL-4/IL-13-deficient mice reveal a critical role of innate immune cells for protective immunity against gastrointestinal helminths. Mucosal Immunol. 2014 Oct 22.
  23. Schwartz C, Oeser K, Prazeres da Costa C, Layland L, Voehringer D. T cell-derived IL-4/IL-13 protects mice against fatal Schistosoma mansoni infection independently of basophils. J Immunol. 2014 Oct 1; 193(7):3590-9.